In the Media

Below is a list of recent news and press articles from the past few years related to Vitamin B12, Methylcobalamin, or Pernicious Anaemia, with summaries and links to the sources. The information is drawn from relevant web results focusing on content published within the last few years (up to July 2025).

1. Signs of Vitamin B Deficiency: Tiredness and Lacking Energy

  • Source: Witney Gazette
  • Publication Date: July 7, 2025
  • Summary: This article highlights the importance of Vitamin B12 and folate in maintaining a healthy nervous system, as per NHS guidance. It explains that a deficiency in Vitamin B12 or folate can lead to abnormally large red blood cells, causing anaemia, which impairs oxygen transport in the body. The piece emphasizes the need for prompt diagnosis and treatment of Vitamin B12 or folate deficiency anaemia to prevent complications, noting that some symptoms may occur even without anaemia.
  • Link: Witney Gazette

2. Maybe It’s Not Just Aging. Maybe It’s Anemia.

  • Source: The New York Times
  • Publication Date: June 28, 2025
  • Summary: This article discusses anaemia in older adults, noting that about one-third of cases stem from nutritional deficiencies, including Vitamin B12 or folate. It highlights that anaemia has multiple causes, some more treatable than others, and mentions that effective treatments for Vitamin B12 deficiency-related anaemia are increasingly prescribed, offering relief to many patients.
  • Link: The New York Times

3. Vitamin B12 Benefits, Potential Risks and If You’re Getting Enough

  • Source: CNET
  • Publication Date: June 30, 2025
  • Summary: This piece explores the role of Vitamin B12 as an essential nutrient and its forms, including Methylcobalamin, which is found in meat and dairy. It notes that conditions like pernicious anaemia, celiac disease, and Crohn’s disease can hinder B12 absorption, increasing deficiency risk. The article advises vegans and vegetarians to consider B12 supplements to avoid deficiency and mentions that cyanocobalamin, a synthetic B12 form, is converted to Methylcobalamin in the body.
  • Link: CNET

4. I Thought I Had Dementia Until I Discovered It Was a Vitamin Deficiency

  • Source: The Telegraph
  • Publication Date: June 3, 2025
  • Summary: This personal account describes a woman’s struggle with fatigue, brain fog, and misdiagnoses before being diagnosed with pernicious anaemia, the most common cause of Vitamin B12 deficiency. The article details her severe symptoms, including neurological issues, and her eventual treatment with B12 injections. Now the chief executive of the Pernicious Anaemia Society, she advocates for better awareness and diagnosis of B12 deficiency, highlighting ongoing challenges in healthcare recognition.
  • Link: The Telegraph

5. NICE Guidance on Pernicious Anaemia

  • Source: NHS Networks
  • Publication Date: May 20, 2025
  • Summary: This article discusses the National Institute for Health and Care Excellence (NICE) guideline on Vitamin B12 deficiency, published in March 2024. The guideline provides evidence-based recommendations for diagnosing and managing pernicious anaemia and B12 deficiency in individuals over 16. It emphasizes clinical assessment, laboratory investigations, and treatment protocols to improve patient outcomes.
  • Link: NHS Networks

6. Addressing the Gaps in the Vitamin B12 Deficiency 2024 NICE Guidelines

  • Source: European Journal of Clinical Nutrition (via Nature)
  • Publication Date: February 21, 2025
  • Summary: This perspective piece critiques the 2024 NICE guidelines on Vitamin B12 deficiency, focusing on their implications for pernicious anaemia, the most common non-dietary cause of B12 deficiency. It argues that the guidelines lack clear diagnostic protocols, potentially causing confusion, and calls for better clinician education to enhance recognition and management of pernicious anaemia. The article notes that severe, life-threatening forms of pernicious anaemia are now rare due to improved testing and treatment.
  • Link: Nature

7. Oral Vitamin B12 Supplementation in Pernicious Anemia: A Prospective Cohort Study

  • Source: ScienceDirect
  • Publication Date: Not specified (recent, within the last few years)
  • Summary: This study explores oral cyanocobalamin (a form of Vitamin B12) as an alternative to intramuscular injections for treating pernicious anaemia, which typically impairs B12 absorption due to intrinsic factor deficiency. The study found that 88.5% of patients with pernicious anaemia showed no B12 deficiency after one month of oral supplementation (1000 μg/day), with significant improvements in plasma B12, homocysteine, and methylmalonic acid levels.
  • Link: ScienceDirect

8. False-Normal Vitamin B12 Results in a Patient with Pernicious Anaemia

  • Source: ScienceDirect
  • Publication Date: Not specified (recent, within the last few years)
  • Summary: This article addresses diagnostic challenges in pernicious anaemia, a common autoimmune disorder affecting about 4% of Europeans. It reports a case where false-normal Vitamin B12 test results delayed diagnosis due to interfering anti-intrinsic factor antibodies. The authors recommend using functional assays (e.g., plasma homocysteine or methylmalonic acid) when clinical suspicion of B12 deficiency is high, despite normal B12 levels, to avoid missing cases.
  • Link: ScienceDirect